Welcome to the Center for Functional Cancer Epigenetics (CFCE) at the Dana-Farber Cancer Institute. The CFCE serves as a central resource for DFCI in supporting both unbiased and hypothesis based cancer research involving epigenetics. .
We provide laboratory data analysis expertise to all Dana-Farber and Harvard affiliated schools as well as external academic and industry researchers. We collaborate with multiple investigators across basic and clinical research to develop and execute innovative research involving epigenetics experiments and analyses.
The CFCE includes faculty from a variety of disciplines including cell biology, physiology, cancer biology, human genetics, and computational biology.
The mission for Center for Functional Cancer Epigenetics (CFCE) is to explore the key role that epigenetic alterations and abnormal transcriptional regulation play in the development and progression of cancer. A better understanding of these alterations will lead to better diagnosis for cancer and the potential to contribute to the knowledge required for the development of new therapeutics exploiting epigenetic mechanisms.
The CFCE was founded by Myles Brown and Shirley Liu in 2011 who oversee the overall scientific and operational activities of the Center as co-directors. Other member labs include the Ramesh Shivdasani lab, the Kornelia Polyak Lab, and the Matthew Freedman lab. Henry Long is the Center’s Associate Director.
Working with the CFCE
The CFCE laboratory, sequencing, and data analysis expertise are available to all Dana-Farber and Harvard affiliated schools and hospitals as well as external academic and industry researchers.
We provide following laboratory work for chip-seq, rna-seq, and dna-seq experiments. Given a cell pellet sample, we will perform the QC, immunoprecipitation, clean-up, library construction, sequencing and basic analysis (QC, mapping reads, statistics on the regions identified, annotation and creating genome browser track for data).
Request for Collaborations
For more information or to submit a request for sequencing services please contact us.